Research in the Weiss Laboratory, Dept. of Human Genetics

 

List the link to the Utah Program for Inherited Neuromuscular Disorders (UPIN) at the Eccles Institute of Human Genetics

 

 

Publications from the Weiss Laboratory, Dept. of Human Genetics

 

132 entries « 2 of 3 »

2009

Ma, Ying; Miller, Jennifer C; Crandall, Hillary; Larsen, Eric T; Dunn, Diane M; Weiss, Robert B; Subramanian, Meenakumari; Weis, John H; Zachary, James F; Teuscher, Cory; Weis, Janis J

Interval-specific congenic lines reveal quantitative trait Loci with penetrant lyme arthritis phenotypes on chromosomes 5, 11, and 12. Journal Article

Infection and immunity, 77 (8), pp. 3302–3311, 2009, ISSN: 1098-5522 (Electronic).

Abstract | Links | Tags: Animals, Ankle, Borrelia burgdorferi, Chromosomes, Crosses, Genetic, genetics, Inbred C3H, Inbred C57BL, Lyme Disease, Mice, Oligonucleotide Array Sequence Analysis, pathogenicity, pathology, Phenotype, Quantitative Trait Loci

Baker, Timothy B; Weiss, Robert B; Bolt, Daniel; von Niederhausern, Andrew; Fiore, Michael C; Dunn, Diane M; Piper, Megan E; Matsunami, Nori; Smith, Stevens S; Coon, Hilary; McMahon, William M; Scholand, Mary B; Singh, Nanda; Hoidal, John R; Kim, Su-Young; Leppert, Mark F; Cannon, Dale S

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. Journal Article

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 11 (7), pp. 785–796, 2009, ISSN: 1469-994X (Electronic).

Abstract | Links | Tags: Addictive, Adult, Aged, Behavior, Female, genetics, Haplotypes, Humans, Male, Middle Aged, Nerve Tissue Proteins, Nicotinic, Phenotype, Polymorphism, Receptors, Risk Factors, Single Nucleotide, Smoking, Tobacco Use Disorder, Utah, Wisconsin

Xing, Jinchuan; Watkins, Scott W; Witherspoon, David J; Zhang, Yuhua; Guthery, Stephen L; Thara, Rangaswamy; Mowry, Bryan J; Bulayeva, Kazima; Weiss, Robert B; Jorde, Lynn B

Fine-scaled human genetic structure revealed by SNP microarrays. Journal Article

Genome research, 19 (5), pp. 815–825, 2009, ISSN: 1088-9051 (Print).

Abstract | Links | Tags: Africa, Asia, Eastern, Ethnic Groups, Europe, Genetic Structures, Genetic Variation, genetics, Genome, Genotype, Human, Humans, India, Oligonucleotide Array Sequence Analysis, Polymorphism, Population, Population Dynamics, Single Nucleotide

Hammoud, Sue; Emery, Benjamin R; Dunn, Diane; Weiss, Robert B; Carrell, Douglas T

Sequence alterations in the YBX2 gene are associated with male factor infertility. Journal Article

Fertility and sterility, 91 (4), pp. 1090–1095, 2009, ISSN: 1556-5653 (Electronic).

Abstract | Links | Tags: Amino Acid Substitution, Case-Control Studies, Cohort Studies, DNA Mutational Analysis, Gene Frequency, Genetic Linkage, genetics, Genotype, Humans, Infertility, Male, metabolism, physiology, Polymorphism, Protamines, RNA-Binding Proteins, Single Nucleotide, Spermatogenesis

Gurvich, Olga L; Maiti, Baijayanta; Weiss, Robert B; Aggarwal, Gaurav; Howard, Michael T; Flanigan, Kevin M

DMD exon 1 truncating point mutations: amelioration of phenotype by alternative translation initiation in exon 6. Journal Article

Human mutation, 30 (4), pp. 633–640, 2009, ISSN: 1098-1004 (Electronic).

Abstract | Links | Tags: Animals, Cell Line, Codon, Duchenne, Dystrophin, Exons, Fluorescent Antibody Technique, genetics, Humans, Immunoblotting, Initiator, Luciferases, metabolism, Muscles, Muscular Dystrophy, Nonsense, pathology, Phenotype, Point Mutation, Protein Biosynthesis, Recombinant Fusion Proteins

Garrone, Nicholas F; Blazer-Yost, Bonnie L; Weiss, Robert B; Lalouel, Jean-Marc; Rohrwasser, Andreas

A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain. Journal Article

BMC cell biology, 10 , pp. 26, 2009, ISSN: 1471-2121 (Electronic).

Abstract | Links | Tags: Amino Acid Sequence, Animals, Calcium, Endosomal Sorting Complexes Required for Transport, Epithelial Sodium Channels, Genetic, genetics, Humans, Ionomycin, metabolism, Molecular Sequence Data, Nedd4 Ubiquitin Protein Ligases, pharmacology, Polymorphism, Protein Isoforms, Protein Structure, Tertiary, Transfection, Ubiquitin-Protein Ligases, Ubiquitination, Xenopus laevis, Xenopus Proteins

2008

Debnath, I; Roundy, K M; Dunn, D M; Weiss, R B; Weis, J J; Weis, J H

Defining a transcriptional fingerprint of murine splenic B-cell development. Journal Article

Genes and immunity, 9 (8), pp. 706–720, 2008, ISSN: 1476-5470 (Electronic).

Abstract | Links | Tags: Animals, B-Cell Activating Factor, B-Cell Activation Factor Receptor, B-Lymphocyte Subsets, Bone Marrow Cells, Cell Differentiation, Gene Expression Profiling, Genetic, genetics, immunology, Inbred Strains, metabolism, Mice, Oligonucleotide Array Sequence Analysis, Signal Transduction, Spleen, Transcription

Ajioka, Richard S; Phillips, John D; Weiss, Robert B; Dunn, Diane M; Smit, Maria W; Proll, Sean C; Katze, Michael G; Kushner, James P

Down-regulation of hepcidin in porphyria cutanea tarda. Journal Article

Blood, 112 (12), pp. 4723–4728, 2008, ISSN: 1528-0020 (Electronic).

Abstract | Links | Tags: 80 and over, Adolescent, Adult, Aged, Antimicrobial Cationic Peptides, Child, complications, DNA Mutational Analysis, Down-Regulation, etiology, Female, Gene Expression Profiling, genetics, Hemochromatosis Protein, Hepcidins, Histocompatibility Antigens Class I, Humans, Infant, Liver Diseases, Male, Membrane Proteins, Middle Aged, Oligonucleotide Array Sequence Analysis, physiology, Porphyria Cutanea Tarda, Preschool, Siderosis, Young Adult

Rajasekaran, Namakkal S; Firpo, Matthew A; Milash, Brett A; Weiss, Robert B; Benjamin, Ivor J

Global expression profiling identifies a novel biosignature for protein aggregation R120GCryAB cardiomyopathy in mice. Journal Article

Physiological genomics, 35 (2), pp. 165–172, 2008, ISSN: 1531-2267 (Electronic).

Abstract | Links | Tags: alpha-Crystallin B Chain, Animal, Animals, Arginine, Cardiomyopathies, Gene Expression Profiling, genetics, Glutathione, Glycine, Humans, metabolism, Mice, Models, Oligonucleotide Array Sequence Analysis, Transgenic

Weiss, Robert B; Baker, Timothy B; Cannon, Dale S; von Niederhausern, Andrew; Dunn, Diane M; Matsunami, Nori; Singh, Nanda A; Baird, Lisa; Coon, Hilary; McMahon, William M; Piper, Megan E; Fiore, Michael C; Scholand, Mary Beth; Connett, John E; Kanner, Richard E; Gahring, Lorise C; Rogers, Scott W; Hoidal, John R; Leppert, Mark F

A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. Journal Article

PLoS genetics, 4 (7), pp. e1000125, 2008, ISSN: 1553-7404 (Electronic).

Abstract | Links | Tags: Adolescent, Adult, Age Factors, Cohort Studies, ethnology, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, genetics, Haplotypes, Humans, Logistic Models, Male, Middle Aged, Nerve Tissue Proteins, Nicotinic, Polymorphism, Protein Subunits, Receptors, Risk Factors, Single Nucleotide, Smoking, Tobacco Use Disorder

Bohnsack, John F; Whiting, April; Gottschalk, Marcelo; Dunn, Diane Marie; Weiss, Robert; Azimi, Parvin H; Philips, Joseph 3rd B; Weisman, Leonard E; Rhoads, George G; Lin, Feng-Ying C

Population structure of invasive and colonizing strains of Streptococcus agalactiae from neonates of six U.S. Academic Centers from 1995 to 1999. Journal Article

Journal of clinical microbiology, 46 (4), pp. 1285–1291, 2008, ISSN: 1098-660X (Electronic).

Abstract | Links | Tags: Academic Medical Centers, Bacterial Proteins, Bacterial Typing Techniques, classification, DNA, DNA Transposable Elements, epidemiology, genetics, Humans, Infant, isolation {&} purification, microbiology, Newborn, pathogenicity, Phylogeny, Polymerase Chain Reaction, Population Surveillance, Sequence Analysis, Serotyping, Streptococcal Infections, Streptococcus agalactiae, United States

Rohrwasser, Andreas; Lott, Paul; Weiss, Robert B; Lalouel, Jean-Marc

From genetics to mechanism of disease liability. Journal Article

Advances in genetics, 60 , pp. 701–726, 2008, ISSN: 0065-2660 (Print).

Abstract | Links | Tags: Animals, Genetic Diseases, Genetic Predisposition to Disease, genetics, Heritable, Humans, Inborn, Quantitative Trait, Quantitative Trait Loci

Gurvich, Olga L; Tuohy, Therese M; Howard, Michael T; Finkel, Richard S; Medne, Livija; Anderson, Christine B; Weiss, Robert B; Wilton, Steve D; Flanigan, Kevin M

DMD pseudoexon mutations: splicing efficiency, phenotype, and potential therapy. Journal Article

Annals of neurology, 63 (1), pp. 81–89, 2008, ISSN: 1531-8249 (Electronic).

Abstract | Links | Tags: Adolescent, Adult, Alternative Splicing, Antisense, Cells, Child, Cultured, DNA Mutational Analysis, drug effects, Duchenne, Dystrophin, Exons, Genetic Predisposition to Disease, Genetic Testing, Genetic Therapy, genetics, Genotype, Humans, Insertional, Male, methods, Muscle Fibers, Muscular Dystrophy, Mutagenesis, Mutation, Oligonucleotides, pharmacology, Phenotype, physiopathology, RNA Precursors, RNA Splice Sites, RNA Splicing, Skeletal, therapeutic use, therapy

2007

Wagner, Lori A; Christensen, Clarissa J; Dunn, Diane M; Spangrude, Gerald J; Georgelas, Ann; Kelley, Linda; Esplin, Sean M; Weiss, Robert B; Gleich, Gerald J

EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression. Journal Article

Blood, 109 (12), pp. 5191–5198, 2007, ISSN: 0006-4971 (Print).

Abstract | Links | Tags: 4, 5-Trisphosphate Receptors, Cells, Cultured, Eosinophil Granule Proteins, Eosinophil Major Basic Protein, Eosinophil-Derived Neurotoxin, Eosinophils, Gene Expression Profiling, Gene Expression Regulation, Genetic, genetics, Hematopoietic Stem Cells, Humans, Inositol 1, metabolism, physiology, RNA, Transcription, Untranslated

2006

Crandall, Hillary; Dunn, Diane M; Ma, Ying; Wooten, Mark R; Zachary, James F; Weis, John H; Weiss, Robert B; Weis, Janis J

Gene expression profiling reveals unique pathways associated with differential severity of lyme arthritis. Journal Article

Journal of immunology (Baltimore, Md. : 1950), 177 (11), pp. 7930–7942, 2006, ISSN: 0022-1767 (Print).

Abstract | Links | Tags: Animal, Animals, Borrelia burgdorferi, Disease Models, Gene Expression Profiling, genetics, immunology, Inbred C3H, Inbred C57BL, Lyme Disease, Mice, Oligonucleotide Array Sequence Analysis, Rabbits, Reverse Transcriptase Polymerase Chain Reaction

Hojgaard, Andrias; Close, Rebecca; Dunn, Dianne M; Weiss, Robert B; Weis, Janis J; Weis, John H

Altered localization of CXCL13 expressing cells in mice deficient in Pactolus following an inflammatory stimulus. Journal Article

Immunology, 119 (2), pp. 212–223, 2006, ISSN: 0019-2805 (Print).

Abstract | Links | Tags: Animals, Cells, Chemokine CXCL13, Chemokines, Cultured, CXC, Gene Expression Profiling, Gene Expression Regulation, genetics, immunology, Inbred BALB C, Integrin beta1, Knockout, Lymphocyte Activation, Macrophages, metabolism, methods, Mice, Neutrophil Infiltration, Peritoneal, Peritonitis, Reverse Transcriptase Polymerase Chain Reaction

White, S J; Aartsma-Rus, A; Flanigan, K M; Weiss, R B; Kneppers, A L J; Lalic, T; Janson, A A M; Ginjaar, H B; Breuning, M H; den Dunnen, J T

Duplications in the DMD gene. Journal Article

Human mutation, 27 (9), pp. 938–945, 2006, ISSN: 1098-1004 (Electronic).

Abstract | Links | Tags: Cohort Studies, diagnosis, Duchenne, Dystrophin, Gene Duplication, Genetic Testing, genetics, Humans, methods, Muscular Dystrophy

Prahalad, S; Bohnsack, J F; Jorde, L B; Whiting, A; Clifford, B; Dunn, D; Weiss, R; Moroldo, M; Thompson, S D; Glass, D N; Bamshad, M J

Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid arthritis. Journal Article

Genes and immunity, 7 (6), pp. 468–475, 2006, ISSN: 1466-4879 (Print).

Abstract | Links | Tags: Arthritis, Base Sequence, CCR5, Child, Cohort Studies, Female, Gene Deletion, Genetic, Genetic Predisposition to Disease, genetics, Genotype, Humans, Juvenile, Male, Polymorphism, Preschool, Receptors, Single Nucleotide

Lin, Feng-Ying C; Whiting, April; Adderson, Elisabeth; Takahashi, Shinji; Dunn, Diane Marie; Weiss, Robert; Azimi, Parvin H; Philips, Joseph 3rd B; Weisman, Leonard E; Regan, Joan; Clark, Penny; Rhoads, George G; Frasch, Carl E; Troendle, James; Moyer, Patricia; Bohnsack, John F

Phylogenetic lineages of invasive and colonizing strains of serotype III group B Streptococci from neonates: a multicenter prospective study. Journal Article

Journal of clinical microbiology, 44 (4), pp. 1257–1261, 2006, ISSN: 0095-1137 (Print).

Abstract | Links | Tags: Adult, Antibodies, Bacterial, Bacterial Typing Techniques, blood, classification, epidemiology, Female, genetics, Humans, immunology, Infant, Male, methods, Newborn, pathogenicity, Phylogeny, Prospective Studies, Serotyping, Streptococcal Infections, Streptococcus agalactiae, transmission

Wooding, Stephen; Bufe, Bernd; Grassi, Christina; Howard, Michael T; Stone, Anne C; Vazquez, Maribel; Dunn, Diane M; Meyerhof, Wolfgang; Weiss, Robert B; Bamshad, Michael J

Independent evolution of bitter-taste sensitivity in humans and chimpanzees. Journal Article

Nature, 440 (7086), pp. 930–934, 2006, ISSN: 1476-4687 (Electronic).

Abstract | Links | Tags: Alleles, Animals, Base Sequence, Biological Evolution, Cell Surface, drug effects, G-Protein-Coupled, genetics, Genotype, Gorilla gorilla, Humans, metabolism, Pan troglodytes, pharmacology, Phenotype, Phenylthiourea, physiology, Receptors, Taste

2005

Crandall, Hillary; Ma, Ying; Dunn, Diane M; Sundsbak, Rhianna S; Zachary, James F; Olofsson, Peter; Holmdahl, Rikard; Weis, John H; Weiss, Robert B; Teuscher, Cory; Weis, Janis J

Bb2Bb3 regulation of murine Lyme arthritis is distinct from Ncf1 and independent of the phagocyte nicotinamide adenine dinucleotide phosphate oxidase. Journal Article

The American journal of pathology, 167 (3), pp. 775–785, 2005, ISSN: 0002-9440 (Print).

Abstract | Links | Tags: Animals, Borrelia burgdorferi, Chromosome Mapping, enzymology, Genetic, Genetic Linkage, genetics, immunology, Inbred Strains, Lyme Disease, metabolism, Mice, NADPH Oxidases, pathology, Phagocytes, Phosphoproteins, Polymorphism, Quantitative Trait Loci, Severity of Illness Index

Coon, Hilary; Dunn, Diane; Lainhart, Janet; Miller, Judith; Hamil, Cindy; Battaglia, Agatino; Tancredi, Raffaella; Leppert, Mark F; Weiss, Robert; McMahon, William

Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2). Journal Article

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 135B (1), pp. 42–46, 2005, ISSN: 1552-4841 (Print).

Abstract | Links | Tags: Autistic Disorder, Base Sequence, Brain, chemistry, DNA, DNA Mutational Analysis, enzymology, Female, genetics, Humans, Male, Nuclear Family, Phenotype, Polymorphism, Single Nucleotide, Tryptophan Hydroxylase

Pankow, James S; Dunn, Diane M; Hunt, Steven C; Leppert, Mark F; Miller, Michael B; Rao, D C; Heiss, Gerardo; Oberman, Albert; Lalouel, Jean-Marc; Weiss, Robert B

Further evidence of a quantitative trait locus on chromosome 18 influencing postural change in systolic blood pressure: the Hypertension Genetic Epidemiology Network (HyperGEN) Study. Journal Article

American journal of hypertension, 18 (5 Pt 1), pp. 672–678, 2005, ISSN: 0895-7061 (Print).

Abstract | Links | Tags: Adult, Aged, Chromosomes, Endosomal Sorting Complexes Required for Transport, Female, genetics, Genotype, Human, Humans, Hypertension, Lod Score, Male, Middle Aged, Nedd4 Ubiquitin Protein Ligases, Pair 18, Posture, Quantitative Trait Loci, Systole, Ubiquitin-Protein Ligases

Dent, K M; Dunn, D M; von Niederhausern, A C; Aoyagi, A T; Kerr, L; Bromberg, M B; Hart, K J; Tuohy, T; White, S; den Dunnen, J T; Weiss, R B; Flanigan, K M

Improved molecular diagnosis of dystrophinopathies in an unselected clinical cohort. Journal Article

American journal of medical genetics. Part A, 134 (3), pp. 295–298, 2005, ISSN: 1552-4825 (Print).

Abstract | Links | Tags: chemistry, Codon, Cohort Studies, diagnosis, DNA, DNA Mutational Analysis, Duchenne, Dystrophin, Exons, Frameshift Mutation, Gene Deletion, Gene Duplication, genetics, Humans, Insertional, methods, Missense, Muscular Dystrophy, Mutagenesis, Mutation, Nonsense, Phenotype, Polymorphism, Single-Stranded Conformational

Lampe, A K; Dunn, D M; von Niederhausern, A C; Hamil, C; Aoyagi, A; Laval, S H; Marie, S K; Chu, M-L; Swoboda, K; Muntoni, F; Bonnemann, C G; Flanigan, K M; Bushby, K M D; Weiss, R B

Automated genomic sequence analysis of the three collagen VI genes: applications to Ullrich congenital muscular dystrophy and Bethlem myopathy. Journal Article

Journal of medical genetics, 42 (2), pp. 108–120, 2005, ISSN: 1468-6244 (Electronic).

Abstract | Links | Tags: Collagen Type VI, congenital, DNA Mutational Analysis, Genetic, genetics, Genomics, Humans, methods, Muscular Diseases, Muscular Dystrophies, Mutation, Polymorphism

2004

Livingston, Robert J; von Niederhausern, Andrew; Jegga, Anil G; Crawford, Dana C; Carlson, Christopher S; Rieder, Mark J; Gowrisankar, Sivakumar; Aronow, Bruce J; Weiss, Robert B; Nickerson, Deborah A

Pattern of sequence variation across 213 environmental response genes. Journal Article

Genome research, 14 (10A), pp. 1821–1831, 2004, ISSN: 1088-9051 (Print).

Abstract | Links | Tags: Apoptosis, Cell Cycle, DNA Repair, Environmental Exposure, Exons, Genetic Variation, genetics, Humans, Nucleic Acid, Regulatory Sequences

Cavalcanti, Andre R O; Dunn, Diane M; Weiss, Robert; Herrick, Glenn; Landweber, Laura F; Doak, Thomas G

Sequence features of Oxytricha trifallax (class Spirotrichea) macronuclear telomeric and subtelomeric sequences. Journal Article

Protist, 155 (3), pp. 311–322, 2004, ISSN: 1434-4610 (Print).

Abstract | Links | Tags: Animals, Antisense, Base Composition, Base Sequence, chemistry, DNA, Entropy, genetics, Open Reading Frames, Oxytricha, Protozoan, Telomere

Coon, Hilary; Singh, Nanda; Dunn, Diane; Eckfeldt, John H; Province, Michael A; Hopkins, Paul N; Weiss, Robert; Hunt, Steven C; Leppert, Mark F

TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study. Journal Article

Atherosclerosis, 174 (2), pp. 357–362, 2004, ISSN: 0021-9150 (Print).

Abstract | Links | Tags: Adult, Aged, Carrier Proteins, Case-Control Studies, Cohort Studies, Coronary Artery Disease, epidemiology, Familial Combined, Female, Genetic Linkage, Genetic Predisposition to Disease, genetics, Genotype, Humans, Hyperlipidemia, Incidence, Male, Middle Aged, Polymerase Chain Reaction, Probability, Risk Assessment, Sensitivity and Specificity, Thioredoxins

Gahring, Lorise C; Persiyanov, Karina; Dunn, Diane; Weiss, Robert; Meyer, Erin L; Rogers, Scott W

Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus. Journal Article

The Journal of comparative neurology, 468 (3), pp. 334–346, 2004, ISSN: 0021-9967 (Print).

Abstract | Links | Tags: Acetylcholine, analysis, Animals, Astrocytes, Base Sequence, chemistry, Genetic, genetics, Glutamate Decarboxylase, Hippocampus, Immunohistochemistry, Inbred BALB C, Inbred C3H, Inbred C57BL, Inbred CBA, Inbred DBA, Inbred Strains, Interneurons, metabolism, Mice, Molecular Sequence Data, Neural Inhibition, Nicotinic, Polymorphism, Receptors, Species Specificity

2003

Doak, Thomas G; Cavalcanti, Andre R O; Stover, Nicholas A; Dunn, Diane M; Weiss, Robert; Herrick, Glenn; Landweber, Laura F

Sequencing the Oxytricha trifallax macronuclear genome: a pilot project. Journal Article

Trends in genetics : TIG, 19 (11), pp. 603–607, 2003, ISSN: 0168-9525 (Print).

Links | Tags: Animals, DNA, genetics, Genome, Germline, Micronucleus, Oxytricha, Phylogeny, Sequence Analysis

Padow, Marcus; Lai, Lilin; Deivanayagam, Champion; DeLucas, Lawrence J; Weiss, Robert B; Dunn, Diane M; Wu, Xiaoyun; Kappes, John C

Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): naturally selected mutations in IN augment DNA synthesis. Journal Article

Journal of virology, 77 (20), pp. 11050–11059, 2003, ISSN: 0022-538X (Print).

Abstract | Links | Tags: analysis, Base Sequence, biosynthesis, Cell Line, Chimera, DNA, Genetic, Genetic Complementation Test, genetics, HIV Integrase, HIV Reverse Transcriptase, HIV-1, Humans, Mutation, physiology, Transcription, Viral, Virus Replication

Flanigan, Kevin M; von Niederhausern, Andrew; Dunn, Diane M; Alder, Jonathan; Mendell, Jerry R; Weiss, Robert B

Rapid direct sequence analysis of the dystrophin gene. Journal Article

American journal of human genetics, 72 (4), pp. 931–939, 2003, ISSN: 0002-9297 (Print).

Abstract | Links | Tags: Base Sequence, Cardiomyopathy, Dilated, DNA, Duchenne, Dystrophin, Genetic Counseling, genetics, Humans, methods, Molecular Sequence Data, Muscular Dystrophy, Polymerase Chain Reaction, Sequence Analysis

2002

Wooding, S P; Watkins, W S; Bamshad, M J; Dunn, D M; Weiss, R B; Jorde, L B

DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection. Journal Article

American journal of human genetics, 71 (3), pp. 528–542, 2002, ISSN: 0002-9297 (Print).

Abstract | Links | Tags: 5' Flanking Region, Africa, Alleles, Animals, Asia, Base Sequence, Biological Evolution, Continental Population Groups, Cytochrome P-450 CYP1A2, Europe, Gene Frequency, Genetic, Genetic Variation, genetics, Haplotypes, Hominidae, Humans, Linkage Disequilibrium, Molecular Sequence Data, National Institutes of Health (U.S.), Polymorphism, Selection, Single Nucleotide, United States

Bamshad, Michael J; Mummidi, Srinivas; Gonzalez, Enrique; Ahuja, Seema S; Dunn, Diane M; Watkins, Scott W; Wooding, Stephen; Stone, Anne C; Jorde, Lynn B; Weiss, Robert B; Ahuja, Sunil K

A strong signature of balancing selection in the 5' cis-regulatory region of CCR5. Journal Article

Proceedings of the National Academy of Sciences of the United States of America, 99 (16), pp. 10539–10544, 2002, ISSN: 0027-8424 (Print).

Abstract | Links | Tags: Alleles, Animals, CCR5, Evolution, Gene Frequency, Genetic, genetics, Gorilla gorilla, Humans, Molecular, Nucleic Acid, Pan troglodytes, Receptors, Regulatory Sequences, Selection

Simin, Karl; Scuderi, Anne; Reamey, James; Dunn, Diane; Weiss, Robert; Metherall, James E; Letsou, Anthea

Profiling patterned transcripts in Drosophila embryos. Miscellaneous

2002, ISSN: 1088-9051 (Print).

Abstract | Links | Tags: Animals, chemistry, classification, Complementary, DNA, Drosophila, Embryo, embryology, Gene Expression Profiling, Genes, Genetic, genetics, Insect, Messenger, methods, Nonmammalian, physiology, RNA, Sequence Analysis, Transcription

Dunn, Diane M; Ishigami, Tomoaki; Pankow, James; von Niederhausern, Andrew; Alder, Jonathan; Hunt, Steven C; Leppert, Mark F; Lalouel, Jean-Marc; Weiss, Robert B

Common variant of human NEDD4L activates a cryptic splice site to form a frameshifted transcript. Journal Article

Journal of human genetics, 47 (12), pp. 665–676, 2002, ISSN: 1434-5161 (Print).

Abstract | Links | Tags: Alternative Splicing, Amino Acid, Amino Acid Sequence, Calcium-Binding Proteins, Chromosomes, DNA, Endosomal Sorting Complexes Required for Transport, Exons, Frameshift Mutation, Genetic, genetics, Human, Humans, Hypertension, Introns, Kidney, Ligases, metabolism, Molecular Sequence Data, Nedd4 Ubiquitin Protein Ligases, Pair 18, physiopathology, Polymorphism, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, Sequence Homology, Tissue Distribution, Ubiquitin-Protein Ligases

2001

Papautsky, I; Mohanty, S; Weiss, R; Frazier, A B

High lane density slab-gel electrophoresis using micromachined instrumentation. Journal Article

Electrophoresis, 22 (18), pp. 3908–3915, 2001, ISSN: 0173-0835 (Print).

Abstract | Links | Tags: Agar Gel, analysis, Bromphenol Blue, Coloring Agents, DNA, Electrophoresis, Equipment Design, instrumentation, Microchemistry, Miniaturization, Specimen Handling

Robb, F T; Maeder, D L; Brown, J R; DiRuggiero, J; Stump, M D; Yeh, R K; Weiss, R B; Dunn, D M

Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Journal Article

Methods in enzymology, 330 , pp. 134–157, 2001, ISSN: 0076-6879 (Print).

Links | Tags: Amino Acyl-tRNA Synthetases, Archaeal, chemistry, Codon, DNA Transposable Elements, enzymology, genetics, Genome, metabolism, physiology, Plasmids, Pyrococcus furiosus, Recombinant Proteins, Structure-Activity Relationship

2000

Diruggiero, J; Dunn, D; Maeder, D L; Holley-Shanks, R; Chatard, J; Horlacher, R; Robb, F T; Boos, W; Weiss, R B

Evidence of recent lateral gene transfer among hyperthermophilic archaea. Journal Article

Molecular microbiology, 38 (4), pp. 684–693, 2000, ISSN: 0950-382X (Print).

Abstract | Tags: Amino Acid Sequence, Archaeal, DNA Transposable Elements, Gene Transfer, Genes, genetics, Genome, Horizontal, Molecular Sequence Data, Pyrococcus furiosus, Sequence Alignment, Thermococcus

Papautsky, I; Brazzle, J; Swerdlow, H; Weiss, R; Frazier, A B

Micromachined pipette arrays. Journal Article

IEEE transactions on bio-medical engineering, 47 (6), pp. 812–819, 2000, ISSN: 0018-9294 (Print).

Abstract | Links | Tags: Biochemistry, Clinical Laboratory Techniques, Electrophoresis, Equipment Design, instrumentation, methods, Polyacrylamide Gel

Ma, K; Weiss, R; Adams, M W

Characterization of hydrogenase II from the hyperthermophilic archaeon Pyrococcus furiosus and assessment of its role in sulfur reduction. Journal Article

Journal of bacteriology, 182 (7), pp. 1864–1871, 2000, ISSN: 0021-9193 (Print).

Abstract | Links | Tags: Amino Acid Sequence, analysis, Base Sequence, Catalysis, chemistry, Cloning, Electron Spin Resonance Spectroscopy, enzymology, Flavin-Adenine Dinucleotide, genetics, Hydrogen, Hydrogen Sulfide, isolation {&} purification, Kinetics, metabolism, Molecular, Molecular Sequence Data, Molecular Weight, NAD, NADP, Nickel, Oxidation-Reduction, Oxidoreductases, Protons, Pyrococcus, Sequence Analysis, Substrate Specificity, Sulfides, Sulfur

1999

Stump, M D; Cherry, J L; Weiss, R B

The use of modified primers to eliminate cycle sequencing artifacts. Journal Article

Nucleic acids research, 27 (23), pp. 4642–4648, 1999, ISSN: 0305-1048 (Print).

Abstract | Links | Tags: Artifacts, Base Sequence, DNA Primers, Hot Temperature, methods, Nucleic Acid Hybridization, Polymerase Chain Reaction

Maeder, D L; Weiss, R B; Dunn, D M; Cherry, J L; Gonzalez, J M; DiRuggiero, J; Robb, F T

Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences. Journal Article

Genetics, 152 (4), pp. 1299–1305, 1999, ISSN: 0016-6731 (Print).

Abstract | Tags: Archaeal, Archaeal Proteins, DNA, Evolution, Genes, genetics, Genome, Hot Temperature, Molecular, Nucleic Acid, Pyrococcus, Pyrococcus furiosus, Sequence Homology, Species Specificity

Roy, R; Mukund, S; Schut, G J; Dunn, D M; Weiss, R; Adams, M W

Purification and molecular characterization of the tungsten-containing formaldehyde ferredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus: the third of a putative five-member tungstoenzyme family. Journal Article

Journal of bacteriology, 181 (4), pp. 1171–1180, 1999, ISSN: 0021-9193 (Print).

Abstract | Tags: Aldehyde Oxidoreductases, Aldehydes, Amino Acid, Amino Acid Sequence, analysis, Archaeal, Archaeal Proteins, Enzyme Activation, enzymology, Evolution, Ferredoxins, Genes, genetics, Glyceraldehyde-3-Phosphate Dehydrogenases, isolation {&} purification, metabolism, Metalloproteins, Molecular, Molecular Sequence Data, Multigene Family, Pyrococcus furiosus, Reducing Agents, Sequence Homology, Substrate Specificity, Sulfides, Tungsten

1998

Ghosh, M; Grunden, A M; Dunn, D M; Weiss, R; Adams, M W

Characterization of native and recombinant forms of an unusual cobalt- dependent proline dipeptidase (prolidase) from the hyperthermophilic archaeon Pyrococcus furiosus. Journal Article

Journal of bacteriology, 180 (18), pp. 4781–4789, 1998, ISSN: 0021-9193 (Print).

Abstract | Tags: Amino Acid Sequence, Base Sequence, chemistry, Dipeptidases, enzymology, isolation {&} purification, metabolism, Molecular Sequence Data, Pyrococcus, Recombinant Proteins

1997

Brown, J R; Robb, F T; Weiss, R; Doolittle, W F

Evidence for the early divergence of tryptophanyl- and tyrosyl-tRNA synthetases. Journal Article

Journal of molecular evolution, 45 (1), pp. 9–16, 1997, ISSN: 0022-2844 (Print).

Abstract | Tags: Amino Acid, Amino Acid Sequence, Animals, Archaea, Bacterial, Biological Evolution, DNA, genetics, Humans, Molecular Sequence Data, Phylogeny, Sequence Alignment, Sequence Homology, Tryptophan-tRNA Ligase, Tyrosine-tRNA Ligase

Riera, J; Robb, F T; Weiss, R; Fontecave, M

Ribonucleotide reductase in the archaeon Pyrococcus furiosus: a critical enzyme in the evolution of DNA genomes? Journal Article

Proceedings of the National Academy of Sciences of the United States of America, 94 (2), pp. 475–478, 1997, ISSN: 0027-8424 (Print).

Abstract | Links | Tags: Amino Acid, Amino Acid Sequence, Archaea, Bacterial, Biological Evolution, chemistry, Cysteine, DNA, enzymology, Genes, genetics, isolation {&} purification, Molecular Sequence Data, Ribonucleotide Reductases, RNA, Sequence Alignment, Sequence Homology

1996

Huang, S C; Stump, M D; Weiss, R; Caldwell, K D

Binding of biotinylated DNA to streptavidin-coated polystyrene latex: effects of chain length and particle size. Journal Article

Analytical biochemistry, 237 (1), pp. 115–122, 1996, ISSN: 0003-2697 (Print).

Abstract | Links | Tags: Bacterial Proteins, Base Sequence, Biotin, DNA, Kinetics, metabolism, Molecular Sequence Data, Particle Size, Polystyrenes, Streptavidin

1995

Odelberg, S J; Weiss, R B; Hata, A; White, R

Template-switching during DNA synthesis by Thermus aquaticus DNA polymerase I. Journal Article

Nucleic acids research, 23 (11), pp. 2049–2057, 1995, ISSN: 0305-1048 (Print).

Abstract | Links | Tags: Base Sequence, DNA, DNA Polymerase I, DNA Replication, Genetic, metabolism, methods, Molecular Sequence Data, Polymerase Chain Reaction, Recombinant, Recombination

1994

Wagner, L A; Gesteland, R F; Dayhuff, T J; Weiss, R B

An efficient shine-dalgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coli Journal Article

Journal of Bacteriology, 1994, ISSN: 00219193.

Abstract | Links | Tags:

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